[HTML][HTML] Development of a 3D angiogenesis model to study tumourendothelial cell interactions and the effects of anti-angiogenic drugs

A Amann, M Zwierzina, S Koeck, G Gamerith… - Scientific reports, 2017 - nature.com
model allows us to investigate tumour-stroma interactions in combination with endothelial
cells in a model were cell … a 3D angiogenesis model where targeted anti-angiogenic therapies …

Tissue-engineered 3D tumor angiogenesis models: potential technologies for anti-cancer drug discovery

K Chwalek, LJ Bray, C Werner - Advanced drug delivery reviews, 2014 - Elsevier
… to the development of targeted anti-angiogenic and anti-cancer … source of cells (endothelial
and non-endothelial cells) and … of tumor cells that recruit, interact, and stimulate the growth of …

[HTML][HTML] A Heterogeneous In Vitro Three Dimensional Model of Tumour-Stroma Interactions Regulating Sprouting Angiogenesis

P Correa de Sampaio, D Auslaender, D Krubasik… - PloS one, 2012 - journals.plos.org
… human spheroid-based system consisting of endothelial cells … The model also shows a
response to anti-angiogenic agentsdeveloped the first 3-dimensional in vitro model of tumour

[HTML][HTML] 3D tumor angiogenesis models: recent advances and challenges

SM Bhat, VA Badiger, S Vasishta, J Chakraborty… - Journal of Cancer …, 2021 - Springer
… the qualitative and quantitative expression of pro and anti-angiogenic molecules. As …
on tumor endothelial cell biology. Further, 3-dimensional (3D) cultures were also developed

[HTML][HTML] In vitro 3D Systems to Model Tumor Angiogenesis and Interactions With Stromal Cells

N Brassard-Jollive, C Monnot, L Muller… - Frontiers in cell and …, 2020 - frontiersin.org
… to anti-cancer therapies such as anti-angiogenic, radio-, and … the impact of shear stress and
interstitial flow and growth factor … Endothelial cells are seeded on Cytodex beads (blue) and …

Bioengineered threedimensional co‐culture of cancer cells and endothelial cells: A model system for dual analysis of tumor growth and angiogenesis

GGY Chiew, N Wei, S Sultania, S Lim… - Biotechnology and …, 2017 - Wiley Online Library
development of the 3D co-culture liver cancer model, we proceeded to test our model with
anti-angiogenic drugs … may be due to close interactions between both liver cancer and ECs, …

Studying the influence of angiogenesis in in vitro cancer model systems

LC Roudsari, JL West - Advanced drug delivery reviews, 2016 - Elsevier
… in tumor progression and metastasis, anti-angiogenic therapies … to developing in vitro
tumor angiogenesis models will be … , 2D and 3D endothelial cell migration, 2D and 3D tumor

Modelling approaches for angiogenesis

G Taraboletti, R Giavazzi - European journal of cancer, 2004 - Elsevier
… The anti-angiogenic strategy has led to the development of … The assays can be two- or
three-dimensional, depending on … in the tumour stroma or directly on tumour endothelial cells. …

Establishment of a 3D model of tumor-driven angiogenesis to study the effects of anti-angiogenic drugs on pericyte recruitment

Y Qiu, N Wang, T Guo, S Liu, X Tang, Z Zhong… - Biomaterials …, 2021 - pubs.rsc.org
… In this study, we developed a microcarrier-based 3D model of tumor-driven angiogenesis
composed of endothelial cells, … for investigating the interactions between endothelial cells and …

[HTML][HTML] New artery of knowledge: 3D models of angiogenesis

E Zucchelli, QA Majid, G Foldes - Vascular Biology, 2019 - vb.bioscientifica.com
development, via the differentiation of endothelial cell … , anti-angiogenic therapy targeting
angiogenic growth factors … on endothelial cells and the interactions between endothelial